Expression of Recombinant Human Amelogenin in Iranian Lizard Leishmania and Its Biological Function Assay

@inproceedings{Yadegari2015ExpressionOR,
  title={Expression of Recombinant Human Amelogenin in Iranian Lizard Leishmania and Its Biological Function Assay},
  author={Zahra Yadegari and Mojgan Bandehpour and Bahram Kazemi and Khojasteh Sharifi-Sarasiabi},
  booktitle={Iranian journal of public health},
  year={2015}
}
BACKGROUND Amelogenins are the major components of enamel matrix proteins. Enamel matrix derivatives (EMD) can be used in periodontal diseases to regenerate periodontal tissues. The main aim of this study was to evaluate expression of full-length functional recombinant human amelogenin (rhAm) in Iranian lizard Leishmania (I.L.L.) as an alternative eukaryotic expression system. METHODS Human cDNA encoding a 175-amino acid amelogenin expression cassette was sub cloned into a pLEXSY vector. The… CONTINUE READING
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