Expression of PLK1 and survivin in diffuse large B-cell lymphoma.

  title={Expression of PLK1 and survivin in diffuse large B-cell lymphoma.},
  author={Lin Wei Liu and Min Zhang and Ping Zou},
  journal={Leukemia & lymphoma},
  volume={48 11},
Polo-like kinase 1 (PLK1) belongs to a conservative family of serine/threonine kinase and plays an important role in the process of cell cycle. Survivin is a member of inhibitor of apoptosis protein (IAP) family. We investigated the expression of PLK1 and survivin with immunohistochemical techniques in diffuse large B-cell lymphoma (DLBCL) and assessed their significance as a potent new tumor marker. The expression rate of PLK1 and survivin were 66.7% (26/39) and 82.1% (32/39), respectively… CONTINUE READING


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