Expression of PDX-1 in prostate cancer, prostatic intraepithelial neoplasia and benign prostatic tissue.

@article{Jonmarker2008ExpressionOP,
  title={Expression of PDX-1 in prostate cancer, prostatic intraepithelial neoplasia and benign prostatic tissue.},
  author={Sara Jonmarker and Axel Glaessgen and William D Culp and Pavel Pisa and Rolf Lewensohn and Peter Ekman and Alexander Valdman and Lars Egevad},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2008},
  volume={116 6},
  pages={
          491-8
        }
}
Pancreatic duodenal homeobox 1 (PDX-1), a Hox type transcription factor, is necessary for differentiation of exocrine and endocrine pancreas, and regulates insulin gene transcription. PDX-1 expression was studied by immunohistochemistry on a tissue microarray (TMA) of 289 primary prostate cancers (PCa) from radical prostatectomy (RP) specimens with median follow-up of 48.9 months. We separately arrayed benign prostatic tissue, atrophy, high-grade prostatic intraepithelial neoplasia (HGPIN) and… CONTINUE READING
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