Expression of OCT4 transcription factor in cutaneous neoplasia.

  title={Expression of OCT4 transcription factor in cutaneous neoplasia.},
  author={Terrence M Katona and Steven D Billings and Rodolfo Montironi and Antonio Lopez-Beltran and Liang Cheng},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  volume={15 4},
The OCT4 transcription factor is a marker of pluripotency and is present in embryonic stem cells, primordial germ cells, and several neoplasms including seminoma, dysgerminoma, and embryonal carcinoma. Recently, immunohistochemical expression of OCT4 protein has been described in the cells within the basal layer of normal human and canine epidermis. We have… CONTINUE READING