Expression of Nemo-like kinase after spinal cord injury in rats

@article{Xu2013ExpressionON,
  title={Expression of Nemo-like kinase after spinal cord injury in rats},
  author={Dawei Xu and Wei Zhao and Gang Pan and Ming Wei Qian and Xinhui Zhu and Wei Liu and Gang Cai and Zhiming Cui},
  journal={Journal of Molecular Neuroscience},
  year={2013},
  volume={52},
  pages={410-418}
}
Wnt can induce signal transduction via the canonical pathway, which was involved in many processes in the nervous system. Nemo-like kinase (NLK) acts as a negative regulator of β-catenin/T-cell factor/lymphoid enhancer factor (LEF) and functions downstream of transforming growth factor β-activated kinase-1 in the Wnt signaling pathway. In this study, we performed a spinal cord injury (SCI) test in adult Sprague–Dawley rats and investigated the dynamic changes and role of NLK expression in the… CONTINUE READING
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