Expression of NPP1 is regulated during atheromatous plaque calcification

@inproceedings{Nitschke2011ExpressionON,
  title={Expression of NPP1 is regulated during atheromatous plaque calcification},
  author={Yvonne Nitschke and Simone Hartmann and Giovanni Federico Torsello and R{\"u}diger Horstmann and Harald Seifarth and Gabriele Weissen-Plenz and Frank Rutsch},
  booktitle={Journal of cellular and molecular medicine},
  year={2011}
}
Mutations of the ENPP1 gene encoding ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) are associated with medial calcification in infancy. While the inhibitory role of matrix proteins such as osteopontin (OPN) with respect to atherosclerotic plaque calcification has been established, the role of NPP1 in plaque calcification is not known. We assessed the degree of plaque calcification (computed tomography), NPP1 and OPN localization (immunohistochemistry) and expression (RT-PCR) in a… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Coronary artery calcification and total mortality in elderly men.

  • Journal of the American Geriatrics Society
  • 2007
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL