Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death

@article{Choi2007ExpressionON,
  title={Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death},
  author={Seung-Chul Choi and Suk Ran Yoon and Y. P. Park and Eun Young Song and Jae Wha Kim and Woo Ho Kim and Young Yang and Jong-Seok Lim and Hee Gu Lee},
  journal={Experimental & Molecular Medicine},
  year={2007},
  volume={39},
  pages={705-714}
}
Although N-myc downstream regulated gene 2 (NDRG2) has been known to be a tumor suppressor gene, the function of this gene has not been elucidated. In the present study, we investigated the expression and function of NDRG2 in human gastric cancer. Among seven gastric cancer and two non-cancer cell lines, only two gastric cancer cell lines, SNU-16 and SNU-620, expressed NDRG2, which was detected in the cytoplasm. Interestingly, NDRG2 was highly expressed in normal gastric tissues, but gastric… CONTINUE READING
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