Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma

@article{Lorentzen2007ExpressionON,
  title={Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma},
  author={Anders Blomkild Lorentzen and Lotte Katrine Vogel and Rikke H Lewinsky and Mona S{\ae}b\o and Camilla Furu Skjelbred and Sine Godiksen and Geir S Hoff and Kjell Magne Tveit and Inger Marie Bowitz Lothe and Tone Ikdahl and Elin H. Kure and Cathy Mitchelmore},
  journal={BMC Cancer},
  year={2007},
  volume={7},
  pages={192 - 192}
}
It has recently been shown that NDRG2 mRNA is down-regulated or undetectable in several human cancers and cancer cell-lines. Although the function of NDRG2 is unknown, high NDRG2 expression correlates with improved prognosis in high-grade gliomas. The aim of this study has been to examine NDRG2 mRNA expression in colon cancer. By examining affected and normal tissue from individuals with colorectal adenomas and carcinomas, as well as in healthy individuals, we aim to determine whether and at… CONTINUE READING