Expression of N-myc and c-src during the development of fetal human brain.

  title={Expression of N-myc and c-src during the development of fetal human brain.},
  author={Eileen F. Grady and Michael Schwab and Werner Rosenau},
  journal={Cancer research},
  volume={47 11},
We studied N-myc RNA by in situ hybridization and S1 nuclease protection analysis in human fetal cerebrum, retina, lung, liver, and placenta during the second trimester. High levels of N-myc RNA were found in the early fetal cerebral germinal layer and the primordial cortex, with lower levels in the intermediate layer. After the twentieth week, N-myc expression declined in the attenuated germinal layer, remained high in the undifferentiated outer cortex, but declined in the differentiating… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 14 extracted citations


Publications referenced by this paper.
Showing 1-10 of 57 references

Developmental Neuropathology

Springer Berlin Heidelberg • 1989
View 2 Excerpts

Chromosome localization in 2935 on April 14, 2017

Schwab, H.E.M.. Varmus, +6 authors J. Trent
Nature (Lond.), • 1987
View 1 Excerpt

Differential expression of myc family genes during murine development

K. A. Zimmerman, G. D. Yancopoulos, +9 authors F. W. Alt
Nature (Lond.), • 1986
View 1 Excerpt

Identification and character ization of the NMYC gene product in human neuroblastoma cells by mono clonal antibodies with defined specificities

N. Ikegaki, J. Burkovsky, R. H. Kennett
Proc. Nati. Acad. Sci. USA, • 1986
View 1 Excerpt

Identification and characterization of the protein encoded by the human N-myc oncogene

D. J. Slamon, Boone, +5 authors L. M. Souza
Science (Wash. DC), • 1986
View 1 Excerpt

Nucleotide sequence of the human N-myc gene

Stanton, W I.., M. Schwab, J. M. Bishop
Proc. Nati. Acad. Sci • 1986
View 2 Excerpts

Similar Papers

Loading similar papers…