Expression of Mycoplasma bovis variable surface membrane proteins in the respiratory tract of calves after experimental infection with a clonal variant of Mycoplasma bovis type strain PG45.

@article{Buchenau2010ExpressionOM,
  title={Expression of Mycoplasma bovis variable surface membrane proteins in the respiratory tract of calves after experimental infection with a clonal variant of Mycoplasma bovis type strain PG45.},
  author={Inka Buchenau and François Poumarat and Dominique Le Grand and H Linkner and Renate Rosengarten and Marion Hewicker-Trautwein},
  journal={Research in veterinary science},
  year={2010},
  volume={89 2},
  pages={223-9}
}
The pathomorphological findings and the expression and distribution of variable surface protein antigens (Vsp) of Mycoplasma (M.) bovis were characterised immunohistochemically in lungs of eight calves following inoculation with a Vsp A-expressing clonal variant of M. bovis type strain PG45. Within 48 h post inoculation (p.i.) an innate immune response dominated by macrophages and neutrophils develops. The monoclonal antibodies (mAbs) 1A1 and 1E5 detected M. bovis Vsp antigens in paraffin… CONTINUE READING
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