Expression of MMP-8 and MMP-13 in the development of periradicular lesions.

  title={Expression of MMP-8 and MMP-13 in the development of periradicular lesions.},
  author={Hideyuki Matsui and Masahiro Yamasaki and Kazuhiko Nakata and Kazuharu Amano and Hiroshi Nakamura},
  journal={International endodontic journal},
  volume={44 8},
AIM To elucidate the expressions of MMP-8 and MMP-13 in experimentally induced rat periradicular lesions by means of the reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemical staining. METHODOLOGY Thirty rats were used and periradicular lesions in mandibular first molar teeth were established following pulp exposure. The animals were sacrificed at 0 (no exposure control), 1, 2, 3, 4 and 6 weeks after pulp exposure. The right molars were used for RT-PCR analysis of… CONTINUE READING


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