Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy

@article{Kasuga2008ExpressionOM,
  title={Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy},
  author={Chinatsu Kasuga and Yukiko Nakahara and Satoshi Ueda and Cynthia Hawkins and Michael D. Taylor and Christian A. Smith and James T. Rutka},
  journal={Journal of neurosurgery. Pediatrics},
  year={2008},
  volume={1 4},
  pages={
          305-13
        }
}
OBJECT Cancer testis antigens (CTAs) were initially identified by their ability to elicit autologous T-cell-mediated immune responses in patients with melanoma. The CTA genes are widely expressed in a variety of human cancers, such as melanoma, breast cancer, lung cancer, esophageal cancer, and hepatocellular carcinoma; however, their expression in pediatric brain tumors, such as medulloblastoma (MB), has not been the subject of in-depth analysis. The MAGE proteins are members of the CTA family… CONTINUE READING
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