Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma

  title={Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma},
  author={Niamh C Murphy and Christopher J Scarlett and James G Kench and Eleanor Y M Sum and Davendra Segara and Emily K. Colvin and Jimmy Susanto and P. H. Cosman and C S Lee and Elizabeth A. Musgrove and Robert Lyndsay Sutherland and Geoff J Lindeman and Susan M. Henshall and Jane E. Visvader and Andrew V. Biankin},
  journal={British Journal of Cancer},
  pages={537 - 541}
Identification of a biomarker of prognosis and response to therapy that can be assessed preoperatively would significantly improve overall outcomes for patients with pancreatic cancer. In this study, patients whose tumours exhibited high LMO4 expression had a significant survival advantage following operative resection, whereas the survival of those patients whose tumours had low or no LMO4 expression was not significantly different when resection was compared with operative biopsy alone.