Expression of KAI1/CD82 in distant metastases from estrogen receptor-negative breast cancer.

Abstract

The tetraspanin protein superfamily member KAI1 suppresses tumor growth and metastasis in animal models and is downregulated in various human malignancies. In breast cancer, KAI1 is preferentially lost in estrogen receptor (ER)-positive tumors. Interestingly, most ER-negative primary breast cancers retain KAI1 expression. This study aimed to evaluate… (More)
DOI: 10.1111/j.1349-7006.2009.01231.x

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