Expression of Jun family members in human colorectal adenocarcinoma.

  title={Expression of Jun family members in human colorectal adenocarcinoma.},
  author={Hengbin Wang and Mark Birkenbach and John P Hart},
  volume={21 7},
The products of the Jun family genes, c-Jun, JunB and JunD, are essential components of the activating protein-1 transcription factor complexes that are critically important in the control of cell growth, differentiation and neoplastic transformation. Although increased c-Jun expression has been reported in human colorectal tumors, expression of JunB and JunD in these tumors has not previously been characterized. In the current study, we examined 24 cases of human colorectal adenocarcinoma by… CONTINUE READING
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