Expression of IL-8, IL-6 and IL-1β in Tears as a Main Characteristic of the Immune Response in Human Microbial Keratitis

@inproceedings{Santacruz2015ExpressionOI,
  title={Expression of IL-8, IL-6 and IL-1β in Tears as a Main Characteristic of the Immune Response in Human Microbial Keratitis},
  author={Concepcion Santacruz and Marisela Linares and Yonathan Garfias and Luisa M. Loustaunau and Lenin Pav{\'o}n and Sonia Mayra P{\'e}rez-Tapia and Mar{\'i}a del Carmen Jim{\'e}nez-Mart{\'i}nez},
  booktitle={International journal of molecular sciences},
  year={2015}
}
Corneal infections are frequent and potentially vision-threatening diseases, and despite the significance of the immunological response in animal models of microbial keratitis (MK), it remains unclear in humans. The aim of this study was to describe the cytokine profile of tears in patients with MK. Characteristics of ocular lesions such as size of the epithelial defect, stromal infiltration, and hypopyon were analyzed. Immunological evaluation included determination of interleukine (IL)-1β, IL… CONTINUE READING