Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease.

Abstract

IL-24 is a member of the IL-10 family of cytokines. In this study, we investigated IL-24 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD), and characterized the molecular mechanisms responsible for IL-24 expression in human colonic subepithelial myofibroblasts (SEMFs). IL-24 expression in the IBD mucosa was evaluated by… (More)
DOI: 10.4049/jimmunol.0804169

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@article{Andoh2009ExpressionOI, title={Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease.}, author={Akira Andoh and Makoto Shioya and Atsushi Nishida and Shigeki Bamba and Tomoyuki Tsujikawa and Shokei Kim-Mitsuyama and Yoshihide Fujiyama}, journal={Journal of immunology}, year={2009}, volume={183 1}, pages={687-95} }