[Expression of HLA-DR structure and a membrane-specific antigen by a granulocytopoietic line of acute leukemic blast cells].

Abstract

Blast cells from peripheral blood of 32 patients with acute leukemia were tested for their ability to react with a monoclonal antibody (D1.B6) specific for HLA-DR surface antigen. In order to evaluate the degree of leukemic cell differentiation a monoclonal antibody (R1.B19) specific for the granulocytopoietic lineage was also employed. The results demonstrated that a considerable proportion of blast cell populations expressed the HLA-DR antigen, while only a small fraction of cells expressed the myeloid antigen.

Cite this paper

@article{Palumbo1982ExpressionOH, title={[Expression of HLA-DR structure and a membrane-specific antigen by a granulocytopoietic line of acute leukemic blast cells].}, author={Antonio Palumbo and B Giovinazzo and Filippo Marmont and Giovanni Maria Garbarino and F Paolino and Luigi Pegoraro}, journal={Bollettino della Società italiana di biologia sperimentale}, year={1982}, volume={58 6}, pages={271-4} }