Expression of HE4 in Endometrial Cancer and Its Clinical Significance

  title={Expression of HE4 in Endometrial Cancer and Its Clinical Significance},
  author={Xiao Li and Yiping Gao and Mingzi Tan and Huiyu Zhuang and Jian Gao and Zhenhua Hu and Huimin Wang and Liancheng Zhu and Juanjuan Liu and Bei Lin},
  booktitle={BioMed research international},
The main aims of this study were to determine the expression of human epididymis protein 4 (HE4) in endometrial cancer and to explore the relationships between HE4 expression, clinicopathological parameters, and prognosis. Immunohistochemistry was used to detect HE4 expression in 102 cases of endometrial cancer, 30 cases of endometrial atypical hyperplasia, and 20 cases of normal endometrium. The positive expression rate of HE4 in endometrial carcinoma was 84.62%, significantly higher than 66… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 32 references

SerumHE 4 as a prognosticmarker in endometrial cancer — apopulation based study

A. Hackethal, A. M. Metcalf
Gynecologic Oncology • 2014


J. Li, H. Chen
Mariani et al., “HE4 (WFDC2) promotes tumor growth in endometrial cancer cell lines,” International Journal ofMolecular Sciences, vol. 14, no. 3, pp. 6026–6043 • 2013

The role of novel biomarker HE 4 in endometrial cancer : a case control prospective study

F. Plotti R. Angioli, S. Capriglione
Tumor Biology • 2013

and B

H. Zhuang, J. Gao, Z. Hu, J. Liu, D. Liu
Lin, “Coexpression of Lewis y antigen with human epididymis protein 4 in ovarian epithelial carcinoma,” PLoS ONE, vol. 8, no. 7, Article ID e68994 • 2013
View 2 Excerpts

and J

S. K. Saarelainen, N. Peltonen, T. Lehtimäki, A. Perheentupa, M. H. Vuento
U. Mäenpää, “Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma,”American Journal of Obstetrics and Gynecology, vol. 209, no. 2, pp. 142.e1–142.e6 • 2013
View 2 Excerpts

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