Expression of H-2 and viral antigens and resistance to the antitumor lysis of tunicamycin-treated MBL-2 lymphoma cells.

@article{Colombo1983ExpressionOH,
  title={Expression of H-2 and viral antigens and resistance to the antitumor lysis of tunicamycin-treated MBL-2 lymphoma cells.},
  author={M. P. Colombo and Marco Alessandro Pierotti and Dario Ballinari and Giorgio Parmiani},
  journal={Immunobiology},
  year={1983},
  volume={165 2},
  pages={186-99}
}
The role of protein glycosylation in the tumor lysis mediated by effector cells derived from Moloney-sarcoma-virus(MSV)-immune mice was studied. Treatment of the Moloney-virus-induced H-2b lymphoma target cells, MBL-2, with tunicamycin (TM), an inhibitor of the protein-N-linked glycosilation, was found to cause a loss of susceptibility to lysis by MSV… CONTINUE READING