Expression of Granulocyte Colony‐Stimulating Factor by Human Cell Lines

  title={Expression of Granulocyte Colony‐Stimulating Factor by Human Cell Lines},
  author={J. Devlin and P. Devlin and K. Myambo and M. Lilly and T. Rado and M. Warren},
  journal={Journal of Leukocyte Biology},
We have isolated and expressed a cDNA clone that encodes a human granulocyte colony‐stimulating factor from the MIA PaCa‐2 cell line. A genomic clone of this factor has been isolated from the CHU‐2 cell line and is reported to encode two alternative transcripts [The EMBO J. 5,575, 1986]; one transcript predicts an amino acid sequence identical to that predicted by our MIA PaCa‐2 cDNA clone; the other transcript predicts a similar protein containing a three amino acid residue insertion. To… Expand
Granulocyte Colony-Stimulating Factor
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Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.
  • K. Welte, E. Platzer, +4 authors M. Moore
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1985
Immunological and functional differences between human type I and II colony-stimulating factors.