Expression of Gastrin-Releasing Peptide Receptor in Breast Cancer and Its Association with Pathologic, Biologic, and Clinical Parameters: A Study of 1,432 Primary Tumors.

@article{Morgat2017ExpressionOG,
  title={Expression of Gastrin-Releasing Peptide Receptor in Breast Cancer and Its Association with Pathologic, Biologic, and Clinical Parameters: A Study of 1,432 Primary Tumors.},
  author={Cl{\'e}ment Morgat and Ga{\"e}tan Macgrogan and V{\'e}ronique Brouste and Val{\'e}rie V{\'e}lasco and Nicolas Sevenet and Herv{\'e} R Bonnefoi and Philippe X Fernandez and Marc Debled and Elif Hindi{\'e}},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2017},
  volume={58 9},
  pages={1401-1407}
}
A growing body of evidence suggests that gastrin-releasing peptide receptor (GRPR) might be a valuable target in breast cancer. To understand which patients can be potential candidates for GRPR-based imaging or targeted therapy, we screened invasive breast cancers by immunohistochemistry for the presence and intensity of GRPR expression. Methods: We explored a tissue microarray of 1,432 primary breast tumors from patients who underwent surgery between 2000 and 2005 at Institut Bergonié, without… CONTINUE READING
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