Expression of GST-π gene in human esophageal carcinogenesis

  title={Expression of GST-π gene in human esophageal carcinogenesis},
  author={Fu Baojin and Zhang Yunhan and Wang Yaohe and Gao Dongling and Fu Shuli and Wen Xiaogang and Zhang Sanshen and Wang Jiang},
  journal={Chinese Journal of Cancer Research},
Objective: To investigate the possible role of GST-π in esophageal carcinogenesis. Methods: GST-π expression at mRNA level was studied by in situ hybridization (ISH) and at protein level by immunohistochemistry (IHC). GST-π expression in normal epithelial cells (NC) of the esophagus, hyperplastic cells (HC), dysplastic cells (DC) from grade I to III, carcinoma in situ (CIS) and all the cells in squamous cell carcinomas (SCC) were examined in the same esophageal cancer specimens (n=48) which… CONTINUE READING