Expression of GABA receptors subunits in peripheral blood mononuclear cells is gender dependent, altered in pregnancy and modified by mental health.

@article{Bhandage2015ExpressionOG,
  title={Expression of GABA receptors subunits in peripheral blood mononuclear cells is gender dependent, altered in pregnancy and modified by mental health.},
  author={A K Bhandage and Charlotte Hellgren and Zhe Jin and Einar B {\'O}lafsson and Inger Sundstr{\"o}m-Poromaa and B Birnir},
  journal={Acta physiologica},
  year={2015},
  volume={213 3},
  pages={575-85}
}
AIM The concept of nerve-driven immunity recognizes a link between the nervous and the immune system. γ-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain, and receptors activated by GABA can be expressed by immune cells. Here, we examined whether the expression of GABA receptors and chloride transporters in human peripheral blood mononuclear cells (PBMCs) was influenced by gender, pregnancy or mental health. METHODS We used RT-qPCR to determine the mRNA expression… CONTINUE READING