Corpus ID: 91871490

Expression of G2A, a Receptor for Lysophosphatidylcholine, by Macrophages in Murine, Rabbit, and Human Atherosclerotic Plaques

@article{YoshiyukiRikitake2002ExpressionOG,
  title={Expression of G2A, a Receptor for Lysophosphatidylcholine, by Macrophages in Murine, Rabbit, and Human Atherosclerotic Plaques},
  author={YoshiyukiRikitake and Ken-ichiHirata and TomoyaYamashita and KenjiIwai and SeiichiKobayashi and HiroshiItoh and Masanoriozaki and JunyaEjiri and MasashiShiomi and NobutakaInoue and SeinosukeKawashima and MitsuhiroYokoyama},
  journal={Arteriosclerosis, Thrombosis, and Vascular Biology},
  year={2002}
}
Objective— Lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein, has been demonstrated to induce multiple functional alterations of vasculature that are potentially involved in atherosclerosis. Recently, an orphan G-protein-coupled receptor, G2A, has been identified as a high-affinity receptor for LPC. Although it has been demonstrated that G2A is expressed predominantly in lymphoid tissues and lymphocytes, there are no reports to determine whether… Expand
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