Expression of Four Methionine Sulfoxide Reductases in Staphylococcus aureus

@inproceedings{Singh2012ExpressionOF,
  title={Expression of Four Methionine Sulfoxide Reductases in Staphylococcus aureus},
  author={Kuldeep Singh and Vineet K Singh},
  booktitle={International journal of microbiology},
  year={2012}
}
Staphylococcus aureus possesses three MsrA enzymes (MsrA1, MsrA2, MsrA3) that reduce the S-epimer of methionine sulfoxide (MetO) and an MsrB enzyme that reduces R-MetO. The four msr genes are expressed from three different promoters. The msrA1/msrB genes are coexpressed. To determine the expression pattern of msr genes, three independent reporter strains were constructed where msr promoter was cloned in front of a promoterless lacZ and the resulting construct was integrated in the chromosome… CONTINUE READING
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