Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium.

  title={Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium.},
  author={Kimm J. Hamann and Delbert R. Dorscheid and Franklin D Ko and Amber E. Conforti and Anne I. Sperling and Klaus Friedrich Rabe and Steven R White},
  journal={American journal of respiratory cell and molecular biology},
  volume={19 4},
The cell surface molecule Fas (CD95) is a member of the tumor necrosis factor receptor family. Ligation of the Fas receptor can lead to induction of apoptosis in inflammatory cells. It has been suggested that expression of the Fas receptor and its ligand (FasL) in airway epithelium may modulate the inflammatory response commonly found in asthmatic lungs. We examined Fas and FasL expression on primary human tissues, on bronchial epithelial cells in primary culture, and on the immortalized human… CONTINUE READING


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