Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions

@inproceedings{Davis2016ExpressionOF,
  title={Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions},
  author={Margaret R. Davis and Erik Arner and Cairnan R. E. Duffy and P A De Sousa and Ingrid Dahlman and Peter Arner and Kim M. Summers},
  booktitle={Molecular genetics and metabolism},
  year={2016}
}
Fibrillin-1 is a large glycoprotein encoded by the FBN1 gene in humans. It provides strength and elasticity to connective tissues and is involved in regulating the bioavailability of the growth factor TGFβ. Mutations in FBN1 may be associated with depleted or abnormal adipose tissue, seen in some patients with Marfan syndrome and lipodystrophies. As this lack of adipose tissue does not result in high morbidity or mortality, it is generally under-appreciated, but is a cause of psychosocial… CONTINUE READING
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Transcriptomic analysis of adipogenesis: coexpression of genes with FBN1 in human and mouse Data in Brief Submitted (2016). AC C EP TE D M AN U SC R IP T ACCEPTED MANUSCRIPT

  • M. R. Davis, E. Arner, +4 authors K. M. Summers
  • 2016
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Mehan, A promoter level mammalian expression atlas Nature

  • A.R.R. Forrest, H. Kawaji, +8 authors T.F.C.J. Mungall
  • 2014
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