Expression of Ethanol-Induced Behavioral Sensitization Is Associated with Alteration of Chromatin Remodeling in Mice

@inproceedings{Botia2012ExpressionOE,
  title={Expression of Ethanol-Induced Behavioral Sensitization Is Associated with Alteration of Chromatin Remodeling in Mice},
  author={B{\'e}atrice Botia and R{\'e}mi Legastelois and St{\'e}phanie Alaux-Cantin and Micka{\"e}l Naassila},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Ethanol-induced behavioral sensitization (EIBS) is proposed to play a role in early and recurring steps of addiction. EIBS does not occur uniformly in all animals even from the same inbred strain. Since recent data demonstrate that epigenetic mechanisms are likely to be involved in the development and the persistence of ethanol-related behaviors, we explored the involvement of epigenetic mechanisms in ethanol response after EIBS development. METHODOLOGY DBA/2J mice were i.p… CONTINUE READING
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