Expression of Estrogen Receptor-β Protein in Rodent Ovary.

  title={Expression of Estrogen Receptor-β Protein in Rodent Ovary.},
  author={Susan L. Fitzpatrick and Judith M Funkhouser and Deborah M Sindoni and Panayiotis E Stevis and Darlene C. Deecher and Ashok R Bapat and Istv{\'a}n J. Merchenthaler and Donald E. Frail},
  volume={140 6},
Estrogen is an essential hormone for the LH surge and ovulation. The primary source of estrogen is from ovarian granulosa cells and in rats, estrogen, in turn, increases granulosa cell number and enhances FSH-stimulated gene expression in these cells. Thus, rat granulosa cells both respond to and synthesize estrogen. To further elucidate the mechanisms mediating the actions of estrogen in granulosa cells, we have identified and characterized the estrogen receptor-b (ER-b) subtype in rodent… CONTINUE READING


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