Expression of ErbB-3 and ErbB-4 protooncogene proteins in oral squamous cell carcinoma: a pilot study.

@article{Vicente2003ExpressionOE,
  title={Expression of ErbB-3 and ErbB-4 protooncogene proteins in oral squamous cell carcinoma: a pilot study.},
  author={Juan Carlos de Vicente and I Esteban and Patricia German{\`a} and Antonino German{\`a} and Jose A. Vega},
  journal={Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal},
  year={2003},
  volume={8 5},
  pages={374-81}
}
BACKGROUND To examine the occurrence of ErbB-3 and ErbB- 4 in oral squamous cell carcinoma, as well as investigate statistical correlations between the expression of these protooncogene proteins and clinical and pathological tumor characteristics. STUDY DESIGN Nineteen oral squamous cell carcinomas (SCC) were analyzed using immunohistochemistry. RESULTS Positive immunostaining for ErbB-3 was found in 13/19 (68%) cases and for ErbB-4 in 10/19 (52%). The intensity of immunostaining for ErbB-3… CONTINUE READING

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