Expression of E-cadherin and catenins in invasive mammary carcinomas.

@article{Zschiesche1997ExpressionOE,
  title={Expression of E-cadherin and catenins in invasive mammary carcinomas.},
  author={Wolfgang Zschiesche and Ines Schoenborn and J{\"u}rgen Behrens and Kurt Herrenknecht and F M Hartveit and Peer Lilleng and Walter Birchmeier},
  journal={Anticancer research},
  year={1997},
  volume={17 1B},
  pages={561-7}
}
E-Cadherin has been shown to be an invasion tumor suppressor gene, but few epidemiological studies have revealed relationships between loss of E-cadherin expression and invasive tumor growth and/or metastasis. The adhesive function of E-cadherin is dependent on the integrity of the catenin components which link E-cadherin to the actin filaments. In order to achieve a better correlation between the loss of cell adhesion and metastasis in cancer, we decided to investigate both E-cadherin and the… CONTINUE READING

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E-cadherin expression in invasive breast cancer.

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