Expression of E-cadherin and catenins in invasive mammary carcinomas.

  title={Expression of E-cadherin and catenins in invasive mammary carcinomas.},
  author={Wolfgang Zschiesche and Ines Schoenborn and J{\"u}rgen Behrens and Kurt Herrenknecht and F M Hartveit and Peer Lilleng and Walter Birchmeier},
  journal={Anticancer research},
  volume={17 1B},
E-Cadherin has been shown to be an invasion tumor suppressor gene, but few epidemiological studies have revealed relationships between loss of E-cadherin expression and invasive tumor growth and/or metastasis. The adhesive function of E-cadherin is dependent on the integrity of the catenin components which link E-cadherin to the actin filaments. In order to achieve a better correlation between the loss of cell adhesion and metastasis in cancer, we decided to investigate both E-cadherin and the… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 33 extracted citations

E-cadherin expression in invasive breast cancer.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie • 2008
View 2 Excerpts

Similar Papers

Loading similar papers…