Expression of E and P-cadherin by melanoma cells decreases in progressive melanomas and following ultraviolet radiation.


The purpose of our study was to determine whether the degree of E- and P-cadherin expression in melanomas correlates with the invasive behavior of the clinical lesions from which the cell lines were derived. Cadherins comprise a family of calcium-dependent cellular adhesion molecules expressed on most cell types that form solid tissues. In the human… (More)


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