Expression of DGAT2 in white adipose tissue is regulated by central leptin action.

Abstract

Acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes catalyze the final step in mammalian triglyceride synthesis, and their functions are considered to be involved in the mechanisms of obesity, insulin resistance, and leptin resistance. Insulin receptor substrate-2 (IRS-2)-deficient mice exhibit obesity-associated with hypertrophic adipocytes and leptin… (More)

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Cite this paper

@article{Suzuki2005ExpressionOD, title={Expression of DGAT2 in white adipose tissue is regulated by central leptin action.}, author={Ryo Suzuki and Kazuyuki Tobe and Masashi Aoyama and Kentaro Sakamoto and Mitsuru Ohsugi and Nozomu Kamei and Shigeyuki Nemoto and Atsushi Inoue and Yusuke Ito and Shoko Uchida and Kazuo Hara and Toshimasa Yamauchi and Naoto Kubota and Yasuo Terauchi and Takashi Kadowaki}, journal={The Journal of biological chemistry}, year={2005}, volume={280 5}, pages={3331-7} }