Expression of Cdk5, p35, and Cdk5-associated kinase activity in the developing rat lens.

@article{Gao1997ExpressionOC,
  title={Expression of Cdk5, p35, and Cdk5-associated kinase activity in the developing rat lens.},
  author={Chun Y. Gao and Zahra Zakeri and Yifei Zhu and H Y He and Peggy S. Zelenka},
  journal={Developmental genetics},
  year={1997},
  volume={20 3},
  pages={267-75}
}
We have investigated the expression of Cdk5 and its regulatory subunit, p35, in the developing rat lens from embryonic day 16 (E16) to postnatal day 8 (P8). Reverse transcription and polymerase chain reaction (RT/PCR) detected Cdk5 and p35 mRNA expression in lens epithelial cells and in differentiating lens fibers throughout this developmental period. Subsequent sequencing of the RT/PCR products confirmed their identifies. In sity hybridization with Cdk5 and p35 riboprobes showed especially… CONTINUE READING

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