Expression of CXCR 4 and Its Down-Regulation by IFN-; in Head and Neck Squamous Cell Carcinoma

Abstract

Purpose: The functionalexpressionofCXCR4,whichplays roles incellmigrationandproliferation in response to its unique ligand stromal cell ^ derived factor-1 (SDF-1), hasbeen reported invariety of carcinomas. However, CXCR4 expression and its functional role in head and neck squamous cell carcinomas (HNSCC) remain unclear. In this study, we investigated CXCR4… (More)

10 Figures and Tables

Topics

  • Presentations referencing similar topics