Expression of CXCR 4 and Its Down-Regulation by IFN-; in Head and Neck Squamous Cell Carcinoma


Purpose: The functionalexpressionofCXCR4,whichplays roles incellmigrationandproliferation in response to its unique ligand stromal cell ^ derived factor-1 (SDF-1), hasbeen reported invariety of carcinomas. However, CXCR4 expression and its functional role in head and neck squamous cell carcinomas (HNSCC) remain unclear. In this study, we investigated CXCR4… (More)

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