Expression of CD90, CD96, CD117, and CD123 on different hematopoietic cell populations from pediatric patients with acute myeloid leukemia.

@article{ChvezGonzlez2014ExpressionOC,
  title={Expression of CD90, CD96, CD117, and CD123 on different hematopoietic cell populations from pediatric patients with acute myeloid leukemia.},
  author={Antonieta Ch{\'a}vez-Gonz{\'a}lez and Elisa Mar{\'i}a Dorantes-Acosta and Dafne Moreno-Lorenzana and Antonio Alvarado-Moreno and Lourdes Andrea Arriaga-Pizano and Hector Mayani},
  journal={Archives of medical research},
  year={2014},
  volume={45 4},
  pages={343-50}
}
BACKGROUND AND AIMS In trying to contribute to our knowledge on the biology of hematopoietic stem cells (HSC) and hematopoietic progenitor cells (HPC) from pediatric acute myeloid leukemia (AML), in the present study we analyzed the expression of four cell surface antigens relevant to human hematopoiesis-CD90, CD96, CD117, and CD123-in bone marrow from pediatric AML patients and normal control subjects. METHODS CD34(+) CD38(-) cells (enriched for HSC) and CD34(+) CD38(+) cells (enriched for… CONTINUE READING