Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity.

@article{Crispn2010ExpressionOC,
  title={Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity.},
  author={Jos{\'e} Carlos Crisp{\'i}n and Brendan T. Keenan and Michele D Finnell and Bonnie L. Bermas and Peter S Schur and Elena M. Massarotti and Elizabeth W. Karlson and Lisa M. Fitzgerald and Sukran Ergin and Vasileios C Kyttaris and George C Tsokos and Karen H Costenbader},
  journal={Arthritis and rheumatism},
  year={2010},
  volume={62 5},
  pages={1431-7}
}
OBJECTIVE To quantify the expression of CD44 and variant isoforms CD44v3 and CD44v6 on T cells from patients with systemic lupus erythematosus (SLE), and to assess correlations of the level of expression of these molecules with disease manifestations. METHODS Information on clinical and demographic characteristics was collected, and blood samples were obtained from 72 patients with SLE and 32 healthy control subjects matched to the patients by sex, race, and age. Expression of CD44 and… CONTINUE READING
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