Expression of CD44 is associated with a metastatic pattern of human neuroblastoma cells in a SCID mouse xenograft model.

@article{Valentiner2008ExpressionOC,
  title={Expression of CD44 is associated with a metastatic pattern of human neuroblastoma cells in a SCID mouse xenograft model.},
  author={Ursula Valentiner and Fried-Ulrich Valentiner and Udo Schumacher},
  journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine},
  year={2008},
  volume={29 3},
  pages={152-60}
}
Expression of CD44, a transmembrane glycoprotein involved in cell-cell and cell-matrix interactions, has been associated with growth and metastatic behavior in several malignant tumors. In contrast to most other malignancies, in which up-regulation of CD44 is related to tumor progression, the absence of CD44 expression characterizes the aggressiveness of… CONTINUE READING