Expression of CD4+ T cell cytokine genes in the colorectal mucosa of inflammatory colorectal polyps in miniature dachshunds.

@article{Ohta2013ExpressionOC,
  title={Expression of CD4+ T cell cytokine genes in the colorectal mucosa of inflammatory colorectal polyps in miniature dachshunds.},
  author={Hiroshi Ohta and Kanae Takada and Shidow Torisu and Masashi Yuki and Yu Tamura and Nozomu Yokoyama and Tatsuyuki Osuga and Sue Yee Lim and Masahiro Murakami and Noboru Sasaki and Kensuke Nakamura and Masahiro Yamasaki and Mitsuyoshi Takiguchi},
  journal={Veterinary immunology and immunopathology},
  year={2013},
  volume={155 4},
  pages={259-63}
}
Inflammatory colorectal polyps (ICRPs) in miniature dachshunds are recently recognized as a major cause of large bowel diarrhea in this dog breed in Japan. ICRPs are characterized by the formation of multiple small polyps and a space-occupying large polyp in the colorectal area, and are thought to be a novel form of inflammatory bowel disease (IBD). In humans, specific cytokine patterns attributed to T helper (Th)1, Th17 and regulatory T cells have important roles in the pathogenesis of IBD… CONTINUE READING

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