Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration.

@article{Wang2010ExpressionOB,
  title={Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration.},
  author={Ju-feng Wang and Ying Liu and Wen-Jing Liu and Suyu He},
  journal={Chinese journal of cancer},
  year={2010},
  volume={29 7},
  pages={
          689-96
        }
}
BACKGROUND AND OBJECTIVE Previous studies have shown that Bmi-1 is overexpressed in a variety of tumors, suggesting that Bmi-1 plays an important role in tumorigenesis. In this study, we investigated the effect of Bim-1 siRNA on cell proliferation, cell cycle, cell apoptosis and migration of human esophageal carcinoma EC9706 cells, and explored its potential mechanisms. METHODS Bmi-1 small interfering RNA (siRNA) was transferred into EC9706 cells. Then, cell proliferation was measured using… Expand
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