Expression of Bilirubin UDP-Glucuronosyltransferase (bUGT) Throughout Fetal Development: Intrasplenic Transplantation into Gunn Rats to Correct Enzymatic Deficiency

@article{Cubero2001ExpressionOB,
  title={Expression of Bilirubin UDP-Glucuronosyltransferase (bUGT) Throughout Fetal Development: Intrasplenic Transplantation into Gunn Rats to Correct Enzymatic Deficiency},
  author={Francisco Cubero and Elvira Arza and Paloma A Maganto and Garc{\'i}a Barrutia and Nieves Mula and Agust{\'i}n Ortiz and Rosa Mar{\'i}a Arahuetes},
  journal={Digestive Diseases and Sciences},
  year={2001},
  volume={46},
  pages={2762-2767}
}
The aim of this work was to determine the pattern of expression of hepatic bilirubin UDP-glucuronosyltransferase throughout fetal development in rats, with the purpose of using fetal hepatocytes at the most appropiate stage of development for transplantation into Gunn rats lacking bilirubin UDP-glucuronosyltransferase activity and then assessing the therapeutic capacity of the implants. %The results show that at day 13 of gestational life there is already bilirubin UDP-glucuronosyltransferase… CONTINUE READING

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