Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders.

@article{Vyas1997ExpressionOB,
  title={Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders.},
  author={Sheela Vyas and France Javoy-Agid and Mar{\'i}a Trinidad Herrero and O Strada and F. Boissiere and Ursula Hibner and Yves Agid},
  journal={Journal of neurochemistry},
  year={1997},
  volume={69 1},
  pages={223-31}
}
The expression of the protooncogene bcl-2, an inhibitor of apoptosis in various cells, was examined in the adult human brain. Several experimental criteria were used to verify its presence; mRNA was analyzed by northern blot with parallel experiments in mouse tissues, by RNase protection, and by in situ hybridization histochemistry. Bcl-2 protein was detected by western blot analysis and immunohistochemistry. Two bcl-2 mRNA species were identified in the human brain. The pattern of distribution… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…