Expression of Androgen Receptor Coregulators in Prostate Cancer

@article{Linja2004ExpressionOA,
  title={Expression of Androgen Receptor Coregulators in Prostate Cancer},
  author={Marika J. Linja and Kati P. Porkka and Zhi Juan Kang and Kimmo J. Savinainen and Olli A. J{\"a}nne and Teuvo L.J. Tammela and Robert L. Vessella and Jorma J. Palvimo and Tapio Visakorpi},
  journal={Clinical Cancer Research},
  year={2004},
  volume={10},
  pages={1032 - 1040}
}
Purpose: The androgen receptor (AR)-mediated signaling pathway seems to be essentially involved in the development and progression of prostate cancer. In vitro studies have shown that altered expression of AR coregulators may significantly modify transcriptional activity of AR, suggesting that these coregulators could also contribute to the progression of prostate cancer. Here, our goal was to assess alterations in the expression of the AR coregulators in prostate cancer in vivo. Experimental… Expand
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