Expression of ABC transporters is an unfavorable prognostic factor in laryngeal squamous cell carcinoma.

@article{Shen2011ExpressionOA,
  title={Expression of ABC transporters is an unfavorable prognostic factor in laryngeal squamous cell carcinoma.},
  author={Bin Shen and Dawei Li and Pin Dong and Shang Gao},
  journal={The Annals of otology, rhinology, and laryngology},
  year={2011},
  volume={120 12},
  pages={
          820-7
        }
}
OBJECTIVES Two prominent and well-characterized representatives of adenosine triphosphate-binding cassette (ABC) transporter - breast cancer resistance protein (BCRP or ABCG2) and P-glycoprotein (P-gp or ABCB1) - are known to be membrane transporters associated with multidrug resistance. The aim of this study was to explore the correlation between ABC transporter expression and the clinicopathologic characteristics, proliferative index, and apoptotic index and their prognostic value in… CONTINUE READING
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