Expression of 14-3-3 sigma, cyclin-dependent kinases 2 and 4, p16, and Epstein-Barr nuclear antigen 1 in nasopharyngeal carcinoma.

@article{Huang2014ExpressionO1,
  title={Expression of 14-3-3 sigma, cyclin-dependent kinases 2 and 4, p16, and Epstein-Barr nuclear antigen 1 in nasopharyngeal carcinoma.},
  author={H-H Huang and Chih-Hao Chen and Shih-Che Huang and Chih-Hsun Yang and C B Hwang},
  journal={The Journal of laryngology and otology},
  year={2014},
  volume={128 2},
  pages={134-41}
}
OBJECTIVE The protein 14-3-3 sigma plays a role in cell cycle arrest by sequestering cyclin-dependent kinase 1 cyclin B1 complexes, as well as cyclin-dependent kinases 2 and 4, hence its definition as a cyclin-dependent kinase inhibitor. However, the nature of the interaction between these biological markers in nasopharyngeal carcinoma is unknown. This study aimed to investigate whether altered expression of these markers contributes to nasopharyngeal carcinogenesis. METHODS The study… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Targeted proteomic analysis of 14-3-3sigma in nasopharyngeal carcinoma.

The international journal of biochemistry & cell biology • 2010

14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2005

Similar Papers

Loading similar papers…