Expression of “early” and “late” viral functions in a somatic cell hybrid between a mouse cell and a spontaneous yielder SV 40-transformed Chinese hamster cell

@article{Surez1978ExpressionO,
  title={Expression of “early” and “late” viral functions in a somatic cell hybrid between a mouse cell and a spontaneous yielder SV 40-transformed Chinese hamster cell},
  author={Helena Su{\'a}rez and Ch. Lavialle and S. Estrade and J. St{\'e}venet and R. Cassingena},
  journal={Archives of Virology},
  year={1978},
  volume={56},
  pages={119-133}
}
A somatic cell hybrid (Cl. 6d) was originated from the fusion of mouse (3T3-4E) and spontaneous yielder SV 40-transformed Chinese hamster (CHK/SVLP AG) cells. During the early stages of its history, the Cl. 6d hybrid underwent a rapid chromosome loss, preferentially loosing hamster chromosomes. This was not a constant tendency of the hybrid cells. As the… CONTINUE READING