Expression of "cell-type-specific" markers during rat tracheal epithelial regeneration.

  title={Expression of "cell-type-specific" markers during rat tracheal epithelial regeneration.},
  author={Tomoko K. Shimizu and Paul Nettesheim and Frans Charles Servatius Ramaekers and Scott H. Randell},
  journal={American journal of respiratory cell and molecular biology},
  volume={7 1},
Previous studies showed that Griffonia simplicifolia I-isolectin B4 (GS I-B4) and monoclonal antibodies (mAbs) against keratin 14 labeled basal cells in the adult rat trachea while other mAbs specifically stained secretory and/or ciliated cells. We used these "cell-type-specific" markers to study cellular differentiation during tracheal epithelial regeneration. Denuded tracheal grafts were inoculated with rat tracheal epithelial cells and were implanted in syngeneic hosts. Marker expression was… CONTINUE READING

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