Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee

@article{Fotopoulos2011ExpressionLO,
  title={Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee},
  author={Vasileios Fotopoulos and Athina K. Tzinia and Matthew Tzurbakis and Vasiliki Kalfakakou and Stamatina Levidiotou-Stefanou and Anastasios D. Georgoulis},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2011},
  volume={20},
  pages={1159-1167}
}
PurposeIn cases of septic knee arthritis, there is excess of matrix metalloproteinases (MMPs) over tissue inhibitors of metalloproteinases (TIMPs), due to enhanced expression and activation that are induced by bacteria in comparison with rheumatic or degenerative arthritis. The aim of this study was to explore the expression levels of synovial gelatinase MMP-9 and its specific inhibitor TIMP-1 in septic and aseptic arthritis and their potential use as additional aids to clinical investigation… CONTINUE READING

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