Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer.

@article{Mah2011ExpressionLO,
  title={Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer.},
  author={Vei Mah and Diana M{\'a}rquez and Mohammad Zia Alavi and Erin L. Maresh and Li Zhang and Nam K Yoon and Steve Horvath and Lora Bagryanova and Michael C. Fishbein and David Chia and Richard J Pietras and Lee A. Goodglick},
  journal={Lung cancer},
  year={2011},
  volume={74 2},
  pages={318-25}
}
Estrogen signaling pathways may play a significant role in the pathogenesis of non-small cell lung cancers (NSCLC) as evidenced by the expression of aromatase and estrogen receptors (ERα and ERβ) in many of these tumors. Here we examine whether ERα and ERβ levels in conjunction with aromatase define patient groups with respect to survival outcomes and possible treatment regimens. Immunohistochemistry was performed on a high-density tissue microarray with resulting data and clinical information… CONTINUE READING
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